Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Jiawei Yanghe Decoction
- Development stage
- Phase 2
- Lead developer
- Guangzhou University of Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Jiawei Yanghe Decoction (JWYHD) is an optimized Traditional Chinese Medicine (TCM) formulation derived from the classical Yanghe Decoction (Yanghe Tang). It is traditionally used in clinical practice for the treatment of autoimmune diseases, asthma, and granulomatous disorders such as sarcoidosis and mastitis. Pharmacologically, JWYHD is categorized as a botanical drug combination that modulates the tumor immune microenvironment. Recent studies in non-small cell lung cancer (NSCLC) suggest that JWYHD can enhance the efficacy of radiotherapy by upregulating the expression of chemokines CXCL9 and CXCL11. This upregulation promotes the recruitment and infiltration of CD8+ T cells into the tumor, thereby augmenting the anti-tumor immune response. The formula typically consists of the base Yanghe Decoction ingredients modified with additional herbs to enhance its therapeutic range.
- Other names
- Jiawei Yanghe TangModified Yanghe DecoctionJia-Wei-Yang-He-Tang
02
Targets
EGFR (Epidermal growth factor receptor)STAT3 (Signal Transducer and Activator of Transcription 3)TNFA (Tumor necrosis factor alpha (soluble))VEGFA (Vascular endothelial growth factor A)CXCL9 (C-X-C motif chemokine ligand 9)
Beyond the preview
Go deeper on Jiawei Yanghe Decoction.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Jiawei Yanghe Decoction.