Jiawei Yinchenhao Decoction

Jiawei Yinchenhao Decoction is a modified traditional Chinese medicine (TCM) formula based on the classical "Yinchenhao decoction." The original formula consists of Artemisia capillaris Thunb (Yinchen), Gardenia jasminoides Ellis (Zhizi), and Rheum palmatum L. (Dahuang). The "Jiawei" prefix indicates additional herbs or modifications to the base prescription, tailored for specific clinical needs. This decoction is primarily used for liver-related diseases such as hepatic fibrosis, cholestasis, jaundice, and intrahepatic cholestasis of pregnancy. Its mechanism involves multi-target regulation of apoptosis-related signaling pathways including TNF and PI3K-Akt pathways[1][2][3]. Active components include rhein, kaempferol, quercetin, aloe-emodin, scoparone, luteolin, and others[1][3]. Pharmacological activities include anti-inflammatory effects, inhibition of liver fibrosis progression by modulating hepatocyte apoptosis/proliferation balance[1], reduction in serum markers like ALT/AST/TBIL/DBIL in animal models[2], and improvement in pruritus scores when combined with ursodeoxycholic acid in clinical settings[3].

Brand names

Jiawei Yinchenhao Decoction

Other names

Modified Yinchenhao Decoction加味茵陈蒿汤Jia Wei Yin Chen Hao Tang