Drug intelligence / Profile preview

Jiawei Yougui Pill + Jintiange Capsule

Development stage
Unknown
Lead developer
Ginwa Enterprise Group
Modality
Recombinant Proteins and Enzymes, Peptides, Small Molecules
Administration
Oral
01

Overview

Jiawei Yougui Pill + Jintiange Capsule is a combination therapy used in traditional Chinese medicine (TCM), primarily for the treatment of osteoporosis and related bone disorders, especially those attributed to kidney deficiency and blood stasis syndromes. - **Jiawei Yougui Pill** is a modified version of the classic "Yougui Wan" formula, traditionally used to tonify kidney yang, replenish essence, and strengthen bones. It typically contains herbs such as Rehmannia glutinosa (Shu Di Huang), Cornus officinalis (Shan Zhu Yu), Dioscorea opposita (Shan Yao), Cuscuta chinensis (Tu Si Zi), Eucommia ulmoides (Du Zhong), among others. The "Jiawei" modification often adds herbs to enhance blood circulation or address specific symptoms[6]. - **Jintiange Capsule** is an approved pharmaceutical product developed as a substitute for tiger bone powder. Its main component is bionic tiger bone powder made from peptides and proteins extracted from other animal bones. It has been clinically applied since 2003 for osteoporosis therapy and has demonstrated efficacy in improving bone mineral density, alleviating rheumatoid arthritis symptoms, reducing synovial inflammation, regulating bone metabolism, and modulating serum metabolic profiles[1][4][5]. The combination aims to synergistically improve bone health by both replenishing kidney yang/essence through herbal means and directly supporting bone structure/metabolism via bioactive peptides/proteins.

02

Targets

CALR (Calreticulin)CaM (Calmodulin)

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