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Jiaxing Univ. HDAC6 compound 21j
- Development stage
- Unknown
- Lead developer
- Jiaxing University
01
Overview
Jiaxing Univ. HDAC6 compound 21j: sourced facts only. name: "Particularly, in the enzymatic selectivity assay, compound 21j was identified as a subtype-selective PI3Kα/HDAC6 dual inhibitor (IC50 = 2.9 and 26 nM against PI3Kα and HDAC6, respectively), which displayed high potency against L-363 cell line with IC50 value of 0.17 μM." [PMID:37652098]; target: "Particularly, in the enzymatic selectivity assay, compound 21j was identified as a subtype-selective PI3Kα/HDAC6 dual inhibitor (IC50 = 2.9 and 26 nM against PI3Kα and HDAC6, respectively), which displayed high potency against L-363 cell line with IC50 value of 0.17 μM." [PMID:37652098]; developer: "College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China; College of Medicine, Jiaxing University, Jiaxing 314001, China." [PMID:37652098]
02
Targets
HDAC6 (Histone deacetylase 6)
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