Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
jiechangyan shuan
- Development stage
- Unknown
- Lead developer
- Jinan Kangzhong Pharmaceutical Technology Development
- Modality
- Small Molecules
- Administration
- Rectal
01
Overview
Jiechangyan Shuan is a Traditional Chinese Medicine (TCM) suppository developed for the treatment of ulcerative colitis and chronic proctitis. It is a multi-herbal formulation containing extracts from Sophorae Flavescentis Radix, Sanguisorbae Radix, Galla Chinensis, Indigo Naturalis, Bletillae Rhizoma, and Corydalis Rhizoma. The medication is designed for rectal administration, allowing for high local concentrations of active constituents at the site of colonic inflammation. Its primary mechanism of action involves the inhibition of pro-inflammatory cytokines (such as TNF-α and IL-6) and the modulation of the NF-κB signaling pathway, which reduces mucosal inflammation and promotes the healing of intestinal ulcers. Jinan Kangzhong Pharmaceutical Technology Development Co., Ltd. is a key developer of this formulation, which is widely manufactured and marketed in China for gastrointestinal disorders.
- Brand names
- Jiechangyan Shuan
- Other names
- Colitis SuppositoryJie Chang Yan Shuan
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NF-κB
Beyond the preview
Go deeper on jiechangyan shuan.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on jiechangyan shuan.