Drug intelligence / Profile preview

Jiedu Shengji Ointment

Development stage
Unknown
Lead developer
Jiangsu Province Hospital on Integration of Chinese and Western Medicine
Modality
Small Molecules
Administration
Topical
01

Overview

Jiedu Shengji Ointment is a specialized Traditional Chinese Medicine (TCM) topical formulation developed by the Jiangsu Province Hospital on Integration of Chinese and Western Medicine. It is primarily indicated for the management of hand-foot skin reaction (HFSR), a common dermatological toxicity associated with multi-kinase inhibitors such as sorafenib and apatinib, as well as chemotherapy agents like capecitabine. The ointment is formulated based on TCM principles to clear heat, detoxify, and promote tissue regeneration (Shengji). Pharmacologically, it is believed to alleviate symptoms such as erythema, dysesthesia, and skin fissures by exerting anti-inflammatory effects, improving local microcirculation, and supporting skin barrier repair. It is widely utilized as a hospital-prepared medication within the oncology and dermatology departments of its developing institution.

Brand names
Jiedu Yuji Ointment
Other names
Jiedu Shengji GaoJSG

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