Jiedu Tongluo Huashi Decoction

Jiedu Tongluo Huashi Decoction is a traditional Chinese medicine (TCM) herbal formula used primarily for the treatment of chronic diseases characterized by "dampness," "toxicity," and impaired circulation according to TCM theory. While specific details about the exact composition of this decoction are not provided in the search results, similar formulas under the "Jiedu Tongluo" name have been studied for their effects on diabetic kidney disease, myocardial fibrosis, and other chronic inflammatory or fibrotic conditions[1][3][9]. Mechanistically, these formulas act through multi-target pathways including inhibition of TGF-β1/Smad2/3 signaling and Rho-associated protein kinase (ROCK) pathways to reduce fibrosis and inflammation[3][9]. The decoction is typically composed of multiple herbs with purported actions such as clearing heat/toxins, promoting blood circulation, removing dampness, and supporting organ function. It is not a single pharmaceutical agent but rather a complex mixture prepared according to TCM principles.

Other names

Jiedu Tongluo Huashi Tang解毒通络化湿汤