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Jiedu Tongluo Tiaogan formula granules is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Shenzhen Hospital of Guangzhou University of Traditional Chinese Medicine. It is designed for the treatment of type 2 diabetes mellitus (T2DM), specifically targeting patients exhibiting a defined TCM syndrome pattern. The formula is intended for use as an adjunct to metformin therapy. Its therapeutic rationale is based on the TCM principles of 'Jiedu' (detoxification), 'Tongluo' (unblocking collaterals), and 'Tiaogan' (regulating the liver). Clinical evaluation of the granules involves comparing different dose levels to traditional decoctions to assess glycemic efficacy (HbA1c and blood glucose levels), symptom improvement, and safety.
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