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Jiedu Xiefei Tongluo Recipe
- Development stage
- Unknown
- Lead developer
- Longhua Hospital Shanghai University of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Jiedu Xiefei Tongluo Recipe is a Traditional Chinese Medicine (TCM) formula developed by LongHua Hospital, Shanghai University of Traditional Chinese Medicine. It is primarily indicated for the treatment of severe pneumonia and associated complications, such as myocardial injury. The formula is designed to clear heat, detoxify, drain the lungs, and unblock collaterals. Research, including network pharmacology and clinical biomarker studies, suggests that the recipe exerts its therapeutic effects by mitigating systemic inflammatory responses (cytokine storms) and protecting against oxidative stress. It has been specifically investigated for its efficacy in treating severe viral pneumonia, including cases related to COVID-19, where it has shown potential in reducing levels of cardiac injury markers like Troponin I and NT-proBNP, as well as pro-inflammatory cytokines.
- Other names
- Jiedu Xiefei Tongluo FangJiedu Xiefei Tongluo Decoction
02
Targets
AKT (RAC-alpha serine/threonine-protein kinase)
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