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Jieyu Decoction

Development stage: Preclinical
Lead developer: Shanghai Hospital of Integrated Traditional Chinese and Western Medicine
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Jieyu Decoction is a traditional Chinese medicine (TCM) herbal formula developed for the treatment of migraine and comorbid depression [chictr]. Formulated as an oral decoction, it is designed to harmonize Qi dynamics and alleviate symptoms of both headache and emotional distress. Jieyu Decoction is being evaluated in clinical trials to assess its efficacy in reducing headache severity, improving migraine-specific quality of life, and alleviating depressive symptoms compared to standard pharmacological treatments such as venlafaxine [chictr].

Other names: Jieyu Decotion

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