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Jieyu Xingyang decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by the Affiliated Brain Hospital of Guangzhou Medical University. It is specifically designed to treat erectile dysfunction (ED) in patients with schizophrenia who are experiencing sexual dysfunction as a side effect of antipsychotic medication. The formula's name reflects its therapeutic intent: "Jieyu" (解郁) refers to resolving stagnation or relieving depression, while "Xingyang" (兴阳) refers to invigorating yang or promoting erectile function. As a decoction, it is prepared by boiling a specific combination of medicinal herbs and is administered orally. Clinical research, including registered trials in China, aims to evaluate its efficacy in improving sexual function and overall quality of life in this patient population, potentially by addressing the hormonal and neurotransmitter imbalances (such as hyperprolactinemia) often induced by long-term antipsychotic use.
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