Drug intelligence / Profile preview

Jin-Xin-Kang

Development stage: Unknown
Lead developer: Guangzhou University of Chinese Medicine
Modality: Small Molecules
Administration: Oral

Overview

Jin-Xin-Kang (JXK), also known as Kangxin formula granule, is a traditional Chinese herbal medicine formula developed by Guangzhou University of Chinese Medicine and the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine for the treatment of chronic heart failure (CHF). The formula consists of seven medicinal herbs: *Ginseng quinquefolium*, *Astragali Radix* (*Astragalus membranaceus*), *Salvia miltiorrhiza*, *Descurainiae Semen Lepidii Semen* (*Descurainia sophia*), *Leonuri Herba* (*Leonurus japonicus*), *Cinnamomi Ramulus* (*Cinnamomum cassia*), and *Ilex pubescens*. JXK targets the Calcineurin (CaN)/Dynamin-Related Protein 1 (Drp1) signaling pathway to alleviate heart failure by mitigating mitochondrial dysfunction. Research published in 2024 indicates that JXK can inhibit the CaN/Drp1 pathway, thereby improving mitochondrial function and treating chronic heart failure. Its clinical efficacy has been evaluated in prospective randomized controlled studies, particularly in patients with Qi deficiency and blood stasis.

Brand names: Kangxin Formula Granule
Other names: Kangxin formula granuleKangxin formulaJXK formula

Targets

CN (Calcineurin)DNM1L (Dynamin-related protein 1)

Beyond the preview

Go deeper on Jin-Xin-Kang.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Jin-Xin-Kang.

Explore the full profile