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Jincao Xiaodu Keli

Development stage: Phase 2
Lead developer: Nanning Duoling Biotechnology
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Jincao Xiaodu Keli is an investigational Traditional Chinese Medicine (TCM) granule formulation developed by Nanning Duoling Biotechnology for the treatment of advanced hepatocellular carcinoma (HCC). The product is currently being evaluated in a Phase 1 clinical trial in China (CTR20233226) to assess its safety, tolerability, and preliminary efficacy in patients with liver cancer. As a TCM "Xiaodu" (detoxifying) formula, it is designed to address the complex pathology of advanced malignancy through the synergistic effects of its botanical constituents, although its specific molecular mechanism of action remains undisclosed in public clinical registries.

Brand names: Jincao Xiaodu Keli
Other names: 金草消毒颗粒Jincao Xiaodu Granules

Targets

CASP3 (Caspase-3)

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