Jing Fang Bai Du San

Jing Fang Bai Du San is a classical traditional Chinese medicine (TCM) herbal formula composed of 13 herbs. It is primarily used to treat external wind-cold-dampness syndromes manifesting as fever and chills without sweating, headache, body aches, neck stiffness, cough due to lung-cold or dampness accumulation, early-stage abscesses or sores with redness and swelling. The formula works by inducing sweating (to release the exterior), dispelling wind (to counteract pathogenic influences), alleviating pain, transforming phlegm/mucus, harmonizing the body's surface defenses (wei qi), and supporting recovery from acute respiratory infections. Modern pharmacological studies suggest that its main active ingredients include acacetin, wogonin, and isorhamnetin; network pharmacology analyses indicate potential modulation of targets such as EGFR (epidermal growth factor receptor), PIK3CA (phosphatidylinositol-4 5-bisphosphate 3-kinase catalytic subunit alpha), LCK (lymphocyte-specific protein tyrosine kinase), MAPK1/3/8 (mitogen-activated protein kinases), STAT3 (signal transducer and activator of transcription 3), TNF (tumor necrosis factor), IL2 (interleukin-2) and RELA. These mechanisms may underlie its anti-inflammatory effects in conditions like common cold/influenza or even COVID-19[4][5][7]. The formula does not target a single molecular pathway but acts through multi-component synergy typical for TCM formulas.

Brand names

Jing Fang Bai Du San

Other names

Schizonepeta and Saposhnikovia Powder to Overcome Pathogenic InfluencesSchizonepeta and Ledebouriella CombinationSchizonepeta and Siler FormulaAntiphlogistic Powder of Schizonepeta and LedebouriellaChing Fang Pai Tu SanJing Fang Bai Du Wan