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Jinggong Granules
- Development stage
- Preclinical
- Lead developer
- Fuzhou Changfuxing New Drug Development
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Jinggong Granules is a Traditional Chinese Medicine (TCM) formulation developed by Fuzhou Changfuxing New Drug Development Co., Ltd. for the treatment of uterine fibroids (hysteromyoma). The preparation is designed based on TCM principles of activating blood circulation, resolving stasis, and softening hard masses to dissipate nodules. Clinically, it is intended to reduce the volume of uterine fibroids and alleviate associated symptoms such as menorrhagia, dysmenorrhea, and pelvic pressure. Pharmacological studies of similar TCM preparations for this indication suggest that the mechanism of action involves the modulation of the hypothalamic-pituitary-ovarian axis, leading to a reduction in serum estrogen and progesterone levels or the antagonism of their respective receptors in uterine tissue, thereby inhibiting the proliferation of leiomyoma cells.
- Brand names
- Jinggong Granules
- Other names
- Jinggong Keli静宫颗粒
02
Targets
ER (Estrogen receptor)PR (Progesterone receptor)
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