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jinghong keli
- Development stage
- Preclinical
- Lead developer
- Xinjiang Uygur Autonomous Region Institute of Drug Research
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Jinghong Keli is a Traditional Chinese Medicine (TCM) granule developed by the Xinjiang Uygur Autonomous Region Institute of Drug Research for the treatment of cardiovascular conditions. The formulation is primarily indicated for coronary heart disease and angina pectoris, particularly in patients diagnosed with the TCM pattern of Qi deficiency and blood stasis. The name 'Jinghong' is derived from the Chinese characters for 'refined' (Jing) and 'Honghua' (Safflower), highlighting its core active ingredient, *Carthamus tinctorius*, which is a significant medicinal crop in the Xinjiang region. The drug's therapeutic mechanism involves promoting blood circulation, removing blood stasis, and dredging meridians. Pharmacologically, it is recognized for its ability to dilate coronary arteries, inhibit platelet aggregation, and improve myocardial blood supply, thereby reducing the frequency and severity of ischemic events.
- Brand names
- Jinghong Keli
- Other names
- 精红颗粒Jinghong GranulesRefined Safflower Granules
02
Targets
PTAFR (Platelet-activating factor receptor)NOS3 (eNOS)
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