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Jingxin Zhidong formula
- Development stage
- Unknown
- Modality
- Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
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- Oral
01
Overview
Jingxin Zhidong formula (JXZDF) is a traditional Chinese medicine herbal formulation widely used in China for the treatment of tic disorders, including Tourette syndrome. It is composed of multiple herbal ingredients and has been evaluated in randomized controlled trials for its efficacy and safety compared to standard pharmaceutical treatments such as aripiprazole. Clinical studies have shown that JXZDF can produce significant improvements in tic severity with a lower incidence of adverse events than aripiprazole, suggesting it may be a safer alternative or adjunctive therapy for pediatric patients with tic disorders[1][2][4]. The precise mechanism of action is not fully elucidated but likely involves modulation of neurotransmitter systems and neuroinflammation based on network pharmacology analyses[5].
- Brand names
- Jingxin Zhidong formula
- Other names
- JXZDFJingxin Zhidong Formula
02
Targets
DAT (Dopamine plasma membrane transport protein)GluR (Glutamate receptors)GABAA (Gamma-aminobutyric acid receptor)
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