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jinhong decoction
- Development stage
- Phase 4
- Lead developer
- Longhua Hospital Shanghai University of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Jinhong decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by LongHua Hospital, Shanghai University of Traditional Chinese Medicine, specifically for the treatment of sepsis, severe sepsis, and septic shock. It typically comprises herbs such as *Rheum palmatum* (Dahuang), *Lonicera japonica* (Jinyinhua), and *Sargentodoxa cuneata* (Hongteng). The decoction is designed to improve the 28-day prognosis of septic patients by enhancing organ function, eliminating pathogens, and restoring internal homeostasis. Its mechanism of action involves the inhibition of systemic inflammatory responses, protection of the intestinal mucosal barrier, and modulation of the gut microbiota to prevent bacterial translocation and subsequent multi-organ dysfunction syndrome (MODS).
- Brand names
- Jinhong Tang
- Other names
- Jinhong TangJinhong formula
02
Targets
Interleukin-6/Signal transducer and activator of transcription 3 signaling axisTNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)
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