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jinhua xiaocuo granules
- Development stage
- Unknown
- Lead developer
- Shanghai Huayuan Anhui Guangsheng Pharmaceutical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Jinhua Xiaocuo Granules (金花消痤颗粒) is an approved traditional Chinese medicine (TCM) formulated as granules for oral administration. Developed and manufactured by companies including Shanghai Huayuan Anhui Renji Pharmaceutical and Shanghai Huayuan Anhui Guangsheng Pharmaceutical, it is primarily indicated for the treatment of acne vulgaris (acne) associated with 'heat in the lungs and stomach' according to TCM theory. The formulation consists of a mixture of nine herbal ingredients: Gardenia jasminoides fruit (炒栀子), Lonicera japonica flower (金银花), Scutellaria baicalensis root (炒黄芩), Rheum palmatum root and rhizome (酒炙大黄), Coptis chinensis rhizome (黄连), Platycodon grandiflorus root (桔梗), Mentha haplocalyx (薄荷), Phellodendron amurense bark (黄柏), and Glycyrrhiza uralensis root (甘草). It exerts its therapeutic effects through clearing heat, purging fire, detoxifying, and reducing swelling, which helps alleviate inflammatory acne lesions, sore throat, mouth ulcers, and constipation.
- Brand names
- GuangshengYuanyaoshi广生源药师
- Other names
- Jinhua Xiaocuo Granules金花消痤颗粒
02
Targets
IL8 (C-X-C Motif Chemokine Ligand 8)ESR1 (ERα)IL1B (Interleukin-1 beta)MMP1 (Matrix metalloproteinase-1)MMP3 (Matrix metalloproteinase-3)SPP1 (Osteopontin)
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