Drug intelligence / Profile preview

Jining Medical Univ. GSK-3β compound 41

Development stage
Preclinical
Lead developer
Jining Medical College
01

Overview

Jining Medical Univ. GSK-3β compound 41: sourced facts only. name: "Overall, the pyrrolo[2,3-b]pyridine derivative 41 could serve as a promising GSK-3β inhibitor for treating AD." [PMID:39798400]; target: "Overall, the pyrrolo[2,3-b]pyridine derivative 41 could serve as a promising GSK-3β inhibitor for treating AD." [PMID:39798400]; developer: "Medical Research Center, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, China; School of Clinical Medicine, Jining Medical University, Jining, Shandong, China." [PMID:39798400]; stage: "In vivo efficacy and acute toxicity experiments showed that, 41 effectively ameliorated the dyskinesia in AlCl3-induced zebrafish AD models and exhibited its low-toxicity nature in C57BL/6 mice." [PMID:39798400]

02

Targets

GSK3 (Glycogen synthase kinase 3 beta)

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