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Jining Medical Univ. GSK-3β compound 46
- Development stage
- Unknown
- Lead developer
- Jining Medical College
01
Overview
Jining Medical Univ. GSK-3β compound 46: sourced facts only. name: "Our results indicated that many pyrrolo[2,3-b]pyridine derivatives had strong GSK-3β inhibitory activities, particularly compounds 41, 46 and 54, with the half maximal inhibitory concentrations (IC50) of 0.22, 0.26 and 0.24 nM, respectively, and each of them generally possessed GSK-3β selectivity over 24 structurally similar kinases." [PMID:39798400]; target: "Our results indicated that many pyrrolo[2,3-b]pyridine derivatives had strong GSK-3β inhibitory activities, particularly compounds 41, 46 and 54, with the half maximal inhibitory concentrations (IC50) of 0.22, 0.26 and 0.24 nM, respectively, and each of them generally possessed GSK-3β selectivity over 24 structurally similar kinases." [PMID:39798400]; developer: "Medical Research Center, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, China; School of Clinical Medicine, Jining Medical University, Jining, Shandong, China." [PMID:39798400]
02
Targets
GSK3 (Glycogen synthase kinase 3 beta)
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