Drug intelligence / Profile preview

Jinzhen Oral Solution

Development stage
Phase 2
Lead developer
Jiangsu Kanion Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Jinzhen Oral Solution (also known as Jinzhen Oral Liquid) is a traditional Chinese patent medicine developed and manufactured by Kanion Pharmaceutical. It is a multi-herb botanical mixture consisting of eight components: Bovis Calculus Artifactus (artificial cow bezoar), Fritillaria ussuriensis bulb, Caprae Hircus Cornu (goat horn), rhubarb (Rhei Radix et Rhizoma), baikal skullcap root, Glycyrrhiza uralensis (licorice), Chloriti Lapis, and gypsum. Originating from the pediatric 'Antelope Qingfei Prescription', which dates back over 400 years, Jinzhen Oral Solution is widely used in China for pediatric respiratory and viral illnesses, including acute bronchitis, Mycoplasma pneumoniae pneumonia, influenza-related lung injury, hand, foot and mouth disease (HFMD), and mild to moderate COVID-19. It exerts its therapeutic effects by suppressing the TLR4/MyD88/NF-κB signaling pathway, inhibiting TRPV1 and TRPA1 channels, and reducing inflammatory cytokines such as TNF-α and IFN-γ.

Brand names
Jinzhen Oral LiquidJinzhen Oral Solution
Other names
JINZHEN Granules for Oral SolutionJZOL

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