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jisheng shenqi pill

Development stage: Unknown
Modality: Small Molecules
Administration: Oral

Overview

Jisheng Shenqi Pill is a traditional Chinese medicine (TCM) herbal formula originally recorded in the Song Dynasty text 'Jisheng Fang'. It is an expansion of the classic Jin Kui Shen Qi Wan, specifically formulated by adding *Semen Plantaginis* and *Radix Achyranthis Bidentatae* to enhance diuretic and blood-circulating properties. The formula is primarily used to treat 'Kidney Yang Deficiency' accompanied by water retention, manifesting as edema, dysuria, and coldness in the lower extremities. Modern pharmacological research indicates that the formula acts through a multi-component, multi-target approach to improve renal function, modulate water-electrolyte balance via aquaporin regulation, and provide anti-inflammatory and anti-fibrotic effects in the kidneys. It is a staple patent medicine in China for managing chronic renal conditions and age-related urinary disorders.

Brand names: Tongrentang Jisheng Shenqi WanZhongjing Jisheng Shenqi WanLancangjiang Jisheng Shenqi Wan
Other names: Jisheng Shenqi WanLife-Preserving Kidney Qi PillShenqi Wan with Plantago and AchyranthesJi Sheng Shen Qi Wan

Targets

REN (Renin)AQP2 (Aquaporin-2)TGFB1 (Transforming growth factor Beta-1 proprotein)

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