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JJH201601 liposome
- Development stage
- Unknown
- Lead developer
- Jiangsu Jibeier Pharmaceutical
- Modality
- Small Molecules, Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
JJH201601 liposome is an investigational liposomal formulation of a novel docetaxel derivative (JJH201601) developed by Jiangsu Jibeier Pharmaceutical. Designed to improve the therapeutic index of docetaxel, JJH201601 acts as a tubulin inhibitor that stabilizes microtubules and disrupts cell cycle progression. The liposomal delivery system is engineered to enhance tumor targeting, reduce systemic toxicities, and potentially overcome multidrug resistance mechanisms such as P-glycoprotein-mediated efflux. It is currently undergoing Phase Ib/IIa clinical evaluation for the treatment of advanced solid tumors, including pancreatic cancer, biliary tract cancer, and hepatocellular carcinoma.
- Other names
- JJH201601 liposome for injectionJJH-201601 liposome for injectionJJH 201601 liposome for injection注射用JJH201601脂质体
02
Targets
TUBB (Tubulin (alpha and beta subunits))
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