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JMKX000189 is an orally administered small molecule drug under development primarily for the treatment of moderately to severely active ulcerative colitis and systemic lupus erythematosus. It is being developed by Jemincare (Jiangxi Jemincare Group) and has reached Phase 3 clinical trials for ulcerative colitis in China and Phase 2 trials for systemic lupus erythematosus. The mechanism of action remains undisclosed or unknown in public sources, but it is not described as a novel mechanism. The drug is also being investigated for potential use in stroke, with IND approval reported in the United States[1][2][3][4].
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