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JNJ-90189892 is an investigational antineoplastic drug being developed by Janssen Research & Development for the treatment of relapsed or refractory acute myeloid leukemia (AML) and higher-risk myelodysplastic syndromes (MDS). It is a new molecular entity currently in Phase 1 clinical trials, with its mechanism of action not yet publicly disclosed. The drug is being evaluated in a first-in-human, dose-escalation study to determine safety, tolerability, and preliminary efficacy in patients who have failed prior therapies. The specific modality and molecular target remain undisclosed as of the latest updates[3][7][9].
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