Drug intelligence / Profile preview

jobelyn

Development stage
Phase 2
Lead developer
Health Forever Product
Modality
Small Molecules
Administration
Oral
01

Overview

Jobelyn is a natural dietary supplement derived from the leaf sheath of Sorghum bicolor, an ancient African grain. It is formulated as a potent antioxidant and anti-inflammatory agent with high polyphenol content, particularly anthocyanins and other flavonoids such as apigeninidin. Jobelyn is marketed for its ability to strengthen the immune system, support healthy blood production, improve joint health by inhibiting inflammatory mediators, and provide cellular protection against oxidative stress. Research suggests it may have benefits in conditions like anemia (including in HIV-positive patients), sickle cell disease (by reducing oxidative stress), memory impairment due to chronic stress (via acetylcholinesterase inhibition and reduced corticosterone levels), and potentially psychosis based on animal studies[1][3][4][5]. Its mechanism of action centers on antioxidant activity—scavenging free radicals—and anti-inflammatory effects through cyclooxygenase inhibition[3]. The product is widely used as a nutritional supplement for general wellness.

Brand names
Jobelyn
Other names
Sorghum bicolor leaf powderSorghum bicolor extractSBLS (Sorghum bicolor leaf sheath)
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)Acetylcholinesterase

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