josamycin propionate

Josamycin propionate is a propionate ester of the macrolide antibiotic josamycin. It is a small molecule antibiotic used to treat various bacterial infections, including those of the respiratory tract, skin, and soft tissues. Like other macrolides, it exerts its antibacterial effect by binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis. It is particularly effective against Gram-positive bacteria and some Gram-negative organisms. In China, it is marketed by companies such as Chongqing Southwest Pharmaceutical in formulations like granules for oral administration, often used in pediatric populations due to its improved palatability compared to the base form.

Other names

丙酸交沙霉素Josamycin propionate