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Juanbi Qianggu Formula

Development stage: Unknown
Lead developer: Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Administration: Oral

Overview

Juanbi Qianggu Formula (蠲痹強骨方) is a Traditional Chinese Medicine (TCM) herbal preparation developed by the Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine. It is specifically formulated to treat musculoskeletal and inflammatory joint conditions, such as knee osteoarthritis and rheumatoid arthritis, particularly in patients presenting with the TCM syndrome of liver and kidney deficiency. The formula is designed to alleviate pain, reduce inflammation, and strengthen bone and cartilage structure. It has been evaluated in clinical trials as both a monotherapy and as an adjunct to conventional treatments like methotrexate and celecoxib.

Brand names: Juanbi Qianggu Granules
Other names: 蠲痹強骨方Juanbi Qianggu Granules

Targets

miR-2683-3p (MicroRNA 2683-3p)RIPK2 (Receptor-interacting protein serine/threonine kinase 2)E3 ligase (E3 ubiquitin ligases)Long non-coding RNA ITSN1-2

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