Drug intelligence / Profile preview

jueyin granules + narrow-band ultraviolet B

Development stage
Unknown
Administration
Oral, Topical
01

Overview

This is a combination therapy consisting of Jueyin granules (a traditional Chinese herbal medicine formulation) and narrow-band ultraviolet B (NB-UVB) phototherapy. **Jueyin granules** are composed of seven herbal ingredients including abalone shell, honeysuckle, tree peony bark, dried Rehmannia root, Hedyotis diffusa folium, and turmeric root tuber. They have demonstrated efficacy in reducing symptoms of mild to moderate psoriasis vulgaris by inhibiting keratinocyte proliferation and modulating immune responses. Network pharmacology suggests their effects may be mediated through the vitamin D receptor pathway[2]. **Narrow-band ultraviolet B (NB-UVB)** is a form of phototherapy using UV light at 311–313 nm wavelength. It is an established treatment for inflammatory skin diseases such as psoriasis; it works primarily by suppressing cutaneous cell-mediated immune responses and depleting Langerhans cells and T cells in the epidermis[6][10]. The combination aims to enhance clinical efficacy for moderate-to-severe plaque psoriasis while minimizing side effects compared to monotherapies[1][3][4].

Other names
JYG + NB-UVBJueyin prescription + narrow-band UVBJueyin granules plus NB-UVB phototherapy
02

Targets

VDR (Vitamin D receptor)

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