juglans regia leaf hydroalcoholic extract

Juglans regia leaf hydroalcoholic extract is a botanical preparation derived from the leaves of the walnut tree (Juglans regia L.), typically produced using a 70% ethanol extraction process. It contains a complex mixture of bioactive compounds, including polyphenols, flavonoids such as quercetin-3-O-rhamnoside, and ellagitannins. The extract is primarily studied in academic settings for its anti-inflammatory, antioxidant, and metabolic effects. Its mechanism of action in respiratory conditions involves the upregulation of heme oxygenase-1 (HO-1) and the maintenance of epithelial barrier integrity through increased expression of tight junction proteins, specifically occludin and Zonula occludens-1 (ZO-1). Clinical research has explored its utility in managing cardiovascular risk factors in type 2 diabetes and its protective effects against drug-induced hepatotoxicity and nephrotoxicity.

Other names

Juglans regia leaf extractwalnut leaf hydroalcoholic extracthydroalcoholic extract of Juglans regia L. leaf