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Juhe Huojing Decoction is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Shenzhen Traditional Chinese Medicine Hospital for the treatment of male infertility, specifically targeting patients who have failed at least one in vitro fertilization (IVF) cycle. The decoction is designed to improve semen parameters, reduce sperm DNA fragmentation, and modulate hormonal levels and anti-sperm antibodies. In clinical settings, it has been evaluated in phase 0 studies comparing its efficacy to L-carnitine oral liquid, measuring outcomes such as natural conception rates and subsequent IVF success. As a TCM therapy, its mechanism of action involves a multi-target approach to restore reproductive health and balance TCM-defined syndromes.
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