Drug intelligence / Profile preview

Juhuo

Development stage
Unknown
Lead developer
Beijing New Weipao Pharmaceutical Technology
Modality
Small Molecules
Administration
Oral
01

Overview

Juhuo (WP-101) is an innovative small molecule drug candidate developed by Beijing New Weipao Pharmaceutical Technology for the treatment of chronic non-bacterial prostatitis (also known as Chronic Prostatitis/Chronic Pelvic Pain Syndrome, or CP/CPPS). Classified as a Class 1.1 new drug in China, Juhuo is a non-steroidal anti-inflammatory drug (NSAID) that acts as a prodrug, metabolizing into an active form that inhibits cyclooxygenase enzymes (COX-1 and COX-2). This inhibition reduces the production of pro-inflammatory prostaglandins in the prostate tissue, thereby alleviating pain and urinary symptoms. The drug is specifically designed to achieve high concentrations in the prostate gland, improving efficacy while potentially reducing systemic side effects. It is currently in Phase 3 clinical trials in China.

Brand names
Juhuo
Other names
聚火
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)

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