jujube extract

Jujube extract, derived from the fruit or seeds of Ziziphus jujuba, is a botanical preparation widely utilized in traditional medicine and the nutraceutical industry. Its pharmacological profile is characterized by sedative, anxiolytic, and neuroprotective activities, primarily attributed to bioactive constituents such as jujubosides (saponins), flavonoids (e.g., spinosin), and triterpenic acids. The extract's primary mechanism of action involves the modulation of the GABAergic system, where it acts as a positive allosteric modulator of GABA(A) receptors, thereby enhancing inhibitory neurotransmission to promote sleep and reduce anxiety. Beyond its effects on the central nervous system, jujube extract demonstrates antioxidant properties by scavenging free radicals and anti-inflammatory effects through the inhibition of pro-inflammatory cytokines. It is also investigated for its potential to improve gastrointestinal motility and metabolic health.

Brand names

Ziziphus ExtractRed Date Extract

Other names

Ziziphus jujuba extractChinese date extractRed date extractDa Zao extractSuan Zao Ren extract