Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
JWK008
- Development stage
- Phase 1
- Lead developer
- Genevector
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
JWK008 is a small molecule agonist of Toll-like receptor 7 (TLR7) developed by Jingwukang (Beijing) Pharmaceutical Technology. By targeting TLR7, which is primarily expressed on plasmacytoid dendritic cells (pDCs) and B cells, JWK008 stimulates the innate immune system to produce Type I interferons (IFN-α) and other pro-inflammatory cytokines. This activation enhances the maturation and antigen-presenting capacity of dendritic cells, subsequently promoting the activation and proliferation of cytotoxic T lymphocytes and natural killer (NK) cells to generate a potent anti-tumor immune response. JWK008 is currently in Phase 1 clinical development for the treatment of advanced solid tumors, where it is administered via intravenous infusion.
- Other names
- JWK008JWK-008JWK 008
02
Targets
IDUA (Alpha-L-iduronidase)TLR7 (Toll-like receptor 7)
Beyond the preview
Go deeper on JWK008.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on JWK008.