Drug intelligence / Profile preview

JY108

Development stage
Unknown
Lead developer
Shenzhen Enduring Biotech
Modality
Antibody-Based Therapeutics
01

Overview

JY108: sourced facts only. name: "In this study, a bispecific antibody JY108 was developed to target CD19 and CD3e with much reduced affinities towards both targets (revealed by Biacore assay results)." [DOI:10.1158/1538-7445.am2024-3192]; target: "In this study, a bispecific antibody JY108 was developed to target CD19 and CD3e with much reduced affinities towards both targets (revealed by Biacore assay results)." [DOI:10.1158/1538-7445.am2024-3192]; target: "In this study, a bispecific antibody JY108 was developed to target CD19 and CD3e with much reduced affinities towards both targets (revealed by Biacore assay results)." [DOI:10.1158/1538-7445.am2024-3192]; developer: "1Shenzhen Enduring Biotech, Ltd., Shenzhen, China." [DOI:10.1158/1538-7445.am2024-3192]; modality: "In this study, a bispecific antibody JY108 was developed to target CD19 and CD3e with much reduced affinities towards both targets (revealed by Biacore assay results)." [DOI:10.1158/1538-7445.am2024-3192]; stage: "In addition, JY108 prolonged the survival of animals with Nalm6 brain metastasis more significantly than Blinatumomab at the same dosage." [DOI:10.1158/1538-7445.am2024-3192]

02

Targets

CD19 (B lymphocyte antigen CD19)CD3E (T-cell surface glycoprotein CD3 epsilon chain receptor)

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