Drug intelligence / Profile preview

Kabizi

Development stage
Unknown
Lead developer
Xinqikang Pharmaceutical
Administration
Oral
01

Overview

**Kabizi** is an investigational oral traditional herbal medicine capsule developed by Xinqikang Pharmaceutical for ulcerative colitis, including patients classified with the blue bile humor pattern in Uyghur medicine. It is being evaluated in a randomized, double-blind, double-dummy, multicenter Phase 2 study as monotherapy and in combination with mesalazine versus mesalazine control. In a dextran sulfate sodium-induced rat model of ulcerative colitis, Kabizi capsules reduced inflammatory and pathological measures and were associated with reduced NLRP3 inflammasome-pathway expression; this preclinical finding does not establish direct molecular target binding in humans. ([chinadrugtrials.org.cn](https://www.chinadrugtrials.org.cn/clinicaltrials.searchlist.dhtml?keywords=CTR20251096))

Other names
Kabizi capsules卡比孜胶囊SLZ
02

Targets

NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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