kaempferia galanga extract

Kaempferia galanga extract is a natural product derived from the rhizome of the *Kaempferia galanga L.* plant, a member of the Zingiberaceae family commonly known as aromatic ginger or kencur. The extract's primary bioactive constituent is ethyl-p-methoxycinnamate (EPMC). It is characterized by its anti-inflammatory, antioxidant, and cytotoxic properties. Mechanistically, the extract works by inhibiting neutrophil infiltration and modulating the production of pro-inflammatory cytokines, specifically tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6). Research, particularly at institutions like Thammasat University, has explored its potential therapeutic applications in inflammatory conditions such as osteoarthritis and various malignancies, including cholangiocarcinoma (bile duct cancer) and hepatocellular carcinoma. While not currently an approved pharmaceutical drug, it is utilized in over-the-counter products and is being investigated in advanced delivery systems like solid self-nanoemulsifying drug delivery systems (S-SNEDDS) and fast disintegrating tablets.

Other names

Kaempferia galanga L. extractkencur extractaromatic ginger extractresurrection lily extract