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Kai-Hou-Jian spray
- Development stage
- Unknown
- Lead developer
- Guizhou Sanli Pharmaceutical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
Kai-Hou-Jian spray is a Traditional Chinese Medicine (TCM) product widely used in China for the treatment of upper respiratory and oral inflammatory conditions, including acute pharyngitis, acute tonsillitis, and stomatitis. It is manufactured by Guizhou Sanli Pharmaceutical. The formulation typically includes extracts from *Ardisia crenata*, *Sophora tonkinensis*, and *Menthol*. It exerts anti-inflammatory, analgesic, and antimicrobial effects, providing rapid relief for sore throat symptoms. A specific pediatric version, Kai-Hou-Jian spray (children's type), has been evaluated in multicenter clinical trials (such as ChiCTR2000031599) to confirm its safety and immediate analgesic efficacy in children aged 4–12 years.
- Brand names
- Kai-Hou-Jian
- Other names
- Kai-Hou-Jian spray (children's type)Kaihoujian Penwuji
02
Targets
TRPM8 (Transient receptor potential cation channel subfamily M member 8)
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