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Kangai Jingfang

Development stage: Unknown
Lead developer: Kaken Pharmaceutical
Administration: Oral

Overview

Kangai Jingfang is a traditional Chinese medicine formula, also referred to as Anticancer Essence Formula, that is being investigated for its therapeutic potential in treating advanced colorectal cancer. It is specifically studied for stage III - IV colorectal cancer characterized by spleen deficiency and essence deficiency types. The drug is administered orally.

Other names: Anticancer Essence Formula抗癌精方口服

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)MMP9 (Matrix metalloproteinase-9)VEGFA (Vascular endothelial growth factor A)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)HDAC1 (Histone Deacetylase 1)ESR1 (ERα)TP53 (Cellular Tumor Antigen p53 R175H)TNFR2/PI3K/AKT/NF-κB (Tumor necrosis factor receptor 2/Phosphoinositide 3-kinase/Protein kinase B/Nuclear factor kappa-light-chain-enhancer of activated B cells signaling axis)HSP90AA1 (Heat shock protein HSP90-alpha)AR (Adrenergic receptors)EGFR T790M (Epidermal growth factor receptor T790M mutant)

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