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Kangai Jingfang

Development stage: Unknown
Lead developer: Shanghai Shen Kang Hospital Development Center
Administration: Oral

Overview

Kangai Jingfang is a traditional Chinese medicine formula, also referred to as Anticancer Essence Formula, that is being investigated for its therapeutic potential in treating advanced colorectal cancer. It is specifically studied for stage III - IV colorectal cancer characterized by spleen deficiency and essence deficiency types. The drug is administered orally.

Other names: Anticancer Essence Formula抗癌精方口服

Targets

AR (Adrenergic receptors)EGFR (Epidermal growth factor receptor)ESR1 (ERα)HDAC1 (Histone Deacetylase 1)HSP90AA1 (Heat shock protein HSP90-alpha)MMP9 (Matrix metalloproteinase-9)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)STAT3 (Signal Transducer and Activator of Transcription 3)TNFR2/PI3K/AKT/NF-κB (Tumor necrosis factor receptor 2/Phosphoinositide 3-kinase/Protein kinase B/Nuclear factor kappa-light-chain-enhancer of activated B cells signaling axis)TP53 (Cellular Tumor Antigen p53 R175H)VEGFA (Vascular endothelial growth factor A)

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