Drug intelligence / Profile preview

Kanger Shen Pian

Development stage
Phase 2
Lead developer
Lanzhou Institute of Chemical Physics
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Kanger Shen Pian is a Traditional Chinese Medicine (TCM) botanical drug candidate developed by the Lanzhou Institute of Chemical Physics of the Chinese Academy of Sciences. It is specifically designed for the treatment of chronic glomerulonephritis, particularly for patients presenting with the Damp-Heat and Blood Stasis syndrome (湿热瘀阻证) according to TCM diagnostic criteria. The medication is administered orally in tablet form. Clinical evaluation, including a Phase II trial (CTR20132145), has focused on its efficacy and safety in managing renal inflammation, reducing proteinuria, and improving clinical outcomes in chronic kidney disease patients.

Brand names
Kanger Shen Pian
Other names
康尔肾片
02

Targets

IL-6 (Interleukin 6)TGFB1 (Transforming growth factor Beta-1 proprotein)TNFA (Tumor necrosis factor alpha (soluble))

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