Drug intelligence / Profile preview

Kangfuxiaoyanshuan

Development stage
Unknown
Lead developer
Sunflower Pharmaceutical Group
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Rectal, Vaginal
01

Overview

Kangfuxiaoyanshuan is a Traditional Chinese Medicine (TCM) suppository formulation widely utilized in China for the treatment of gynecological inflammatory conditions, particularly chronic pelvic inflammatory disease (PID), adnexitis, and endometritis. The product is composed of eight botanical ingredients, including *Sophora flavescens*, *Leonurus japonicus*, and *Phellodendron amurense*, which provide a combination of anti-inflammatory, antibacterial, and analgesic properties. It is typically administered rectally or vaginally to deliver active constituents directly to the pelvic region, where it helps to reduce pelvic congestion, alleviate pain, and lower levels of inflammatory cytokines. Clinical studies often evaluate its efficacy both as a monotherapy and in combination with other interventions like physical therapy or antibiotics.

Brand names
Kangfuxiaoyanshuan
Other names
Kangfu Xiaoyan ShuanKangfu Xiaoyan Suppository
02

Targets

ARG1 (Arginase 1)MMP2 (Matrix metalloproteinase-2)NOS2 (Nitric Oxide Synthase 2)NOS3 (eNOS)TGFB1 (Transforming growth factor Beta-1 proprotein)

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