Drug intelligence / Profile preview

Kangliuwan

Development stage
Unknown
Lead developer
Beijing Tong Ren Tang
Modality
Small Molecules
Administration
Oral
01

Overview

Kangliuwan is a Traditional Chinese Medicine (TCM) formulation, classified as a proprietary Chinese medicine (Zhongchengyao), primarily utilized in the treatment of various malignant tumors. It is particularly indicated for brain tumors (such as gliomas), lung cancer, breast cancer, and liver cancer, often serving as an adjuvant therapy to conventional Western treatments like surgery, chemotherapy, and radiotherapy. The formulation is designed based on TCM principles of "softening hardness and dissipating nodules" (ruanjian shengjie) and "clearing heat and detoxifying" (qingre jiedu). Its composition typically includes a complex mixture of herbal and mineral ingredients, such as *Sargassum* (Haizao), *Thallus Laminariae* (Kunbu), *Concha Ostreae* (Muli), and *Prunella vulgaris* (Xiakucao). Modern pharmacological research suggests that Kangliuwan exerts its antineoplastic effects by inducing apoptosis in tumor cells, inhibiting angiogenesis, and modulating the host immune response, although specific molecular targets are pleiotropic and characteristic of multi-component herbal therapies.

Brand names
Kangliuwan
Other names
Anti-tumor pillKang Liu WanKangliu Pill
02

Targets

BCL-2 (BCL-2 family)CASP3 (Caspase-3)VEGFA (Vascular endothelial growth factor A)

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