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KBA-1704
- Development stage
- Preclinical
- Lead developer
- Kling Biotherapeutics
- Modality
- Nucleic Acid-Directed Small Molecules → Small Molecules, Vaccines & Immunotherapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Covalent Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Parenteral (preclinical/early Research Stage)[1]
01
Overview
KBA-1704 is an investigational anti-desmoglein 2 (DSG2) monoclonal antibody therapy developed by Kling Biotherapeutics. It is being studied as an antineoplastic immunotherapy, with its primary mechanism of action involving the inhibition or modulation of desmoglein 2, a cell adhesion molecule implicated in cancer progression. The drug is currently in preclinical development for cancer indications, including colonic cancer and Lynch syndrome II. As a new molecular entity, it represents a novel approach to targeting DSG2 in oncology[1][2].
- Other names
- KBA 1704KBA1704KBA-1704
02
Targets
DSG2 (Desmoglein-2)
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