Drug intelligence / Profile preview

KBP-201

Development stage: Phase 2
Lead developer: Kentucky BioProcessing
Modality: Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

KBP-201 is a plant-based protein subunit vaccine candidate developed by KBio (formerly Kentucky BioProcessing), a subsidiary of British American Tobacco, for the prevention of COVID-19. The vaccine is produced using a transient expression system in *Nicotiana benthamiana* (tobacco plants), where the genetic sequence for the SARS-CoV-2 receptor-binding domain (RBD) is cloned and expressed. It is formulated with a CpG adjuvant to enhance the immune response. KBP-201 is designed to induce neutralizing antibodies against the SARS-CoV-2 spike protein, thereby inhibiting viral entry into host cells. The development program transitioned to KBio Holdings Limited following the incorporation of Kentucky BioProcessing.

Other names: KBP-201 COVID-19 vaccineKBP201 COVID-19 vaccineKBP 201 COVID-19 vaccine

Targets

RBD (SARS-CoV-2 spike receptor-binding domain)

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