Drug intelligence / Profile preview

KC1086

Development stage
Phase 1
Lead developer
Beijing Konruns Pharmaceutical
Modality
Covalent Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

KC1086 is a **potent and highly selective small molecule inhibitor of lysine acetyltransferase 6A (KAT6A) and lysine acetyltransferase 6B (KAT6B)**, developed as an epigenetic therapeutic agent. It is intended for the treatment of advanced, recurrent, or metastatic solid tumors and is being evaluated in interventional clinical trials for safety, tolerability, pharmacokinetics, and preliminary efficacy. The drug is administered orally in cycles, and represents a novel structural class among KAT6 inhibitors, targeting critical epigenetic regulators implicated in oncogenesis[1][3][5][7][9].

Brand names
KC1086KC-1086KC 1086
Other names
KC1086KC-1086KC 1086
02

Targets

KAT6A (Lysine acetyltransferase 6A)KAT6B (Histone acetyltransferase KAT6B)

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