Drug intelligence / Profile preview

KD-019

Development stage
Unknown
Lead developer
Yan'an Affiliated Hospital of Kunming Medical University
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Administration
Intravenous
01

Overview

KD-019 is an investigational autologous chimeric antigen receptor T-cell (CAR-T) therapy targeting the CD19 antigen. Developed by Yan'an Affiliated Hospital of Kunming Medical University, likely in collaboration with the biotechnology company KAEDI, the therapy utilizes synthetic biology to optimize nano-vector T-cell transduction. It is designed to treat B-cell malignancies by genetically modifying a patient's own T cells to express a chimeric antigen receptor that recognizes and binds to CD19-positive cells. This binding triggers T-cell activation and the subsequent immune-mediated destruction of malignant B-cells. KD-019 is currently being evaluated in Phase I clinical trials for the treatment of relapsed or refractory B-cell lymphoma and B-cell acute lymphoblastic leukemia (B-ALL).

Other names
Anti-CD19 CAR-T Cells InjectionAnti-CD-19 CAR-T Cells InjectionAnti-CD 19 CAR-T Cells InjectionKD-019 CAR-TKD019 CAR-TKD 019 CAR-TAnti-CD19 Chimeric Antigen Receptor With Synthetic Biology Optimizing Nano-vector T Cells InjectionAnti-CD-19 Chimeric Antigen Receptor With Synthetic Biology Optimizing Nano-vector T Cells InjectionAnti-CD 19 Chimeric Antigen Receptor With Synthetic Biology Optimizing Nano-vector T Cells Injection
02

Targets

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