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KD-295
- Development stage
- Unknown
- Lead developer
- KM Biologics
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
KD-295 is an inactivated Zika virus vaccine candidate developed by KM Biologics (formerly The Chemo-Sero-Therapeutic Research Institute, also known as Kaketsuken). The vaccine is produced using cell culture-based technology and is designed to prevent Zika virus infection by eliciting a protective immune response. It is administered via intramuscular injection. A Phase 1 clinical trial (jRCT2080221412) was conducted in Japan to evaluate the safety, tolerability, and immunogenicity of the vaccine in healthy adult males, utilizing a two-dose regimen administered 21 days apart at two different dose levels.
- Other names
- Zika virus vaccine
02
Targets
ZIKV E (Zika virus envelope protein)TCR-ZIKV (Zika virus-specific T-cell receptor)prM (Zika virus precursor membrane protein)B-cell receptor specific for Zika virus envelope and pre-membrane proteins (ZIKV E/prM-specific BCR)
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