Drug intelligence / Profile preview

Kechang Granules

Development stage
Unknown
Lead developer
Hangzhou Wang Changgen Liver
Modality
Small Molecules
Administration
Oral
01

Overview

Kechang Granules is a Traditional Chinese Medicine (TCM) candidate developed by Hangzhou Wang Changgen Liver, Gallbladder, and Kidney Traditional Chinese Medicine Technology Co., Ltd. for the treatment of acute bronchitis. It is specifically formulated to address the 'wind-heat invading the lung' syndrome, a common TCM diagnosis for respiratory infections characterized by cough, fever, and yellow sputum. The granules are designed to clear heat, resolve phlegm, and suppress cough. The drug has been evaluated in Phase II clinical trials in China (e.g., CTR20191445) to establish its safety and therapeutic efficacy compared to placebo. As a multi-herb TCM formulation, it likely exerts its effects through a multi-targeted approach involving anti-inflammatory and antitussive mechanisms.

Brand names
Kechang Granules
Other names
Kechang Keli咳畅颗粒
02

Targets

NOS3 (eNOS)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)HSP90AA1 (Heat shock protein HSP90-alpha)

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