Drug intelligence / Profile preview

Keimyung Univ. HDAC6 compound 6e

Development stage
Unknown
Lead developer
Keimyung University
01

Overview

Keimyung Univ. HDAC6 compound 6e: sourced facts only. name: "In particular, compound 6e shows a significant inhibitory activity against both HDAC6 and Hsp90 with IC50 values of 106 nM and 61 nM, respectively." [PMID:35834905]; target: "In particular, compound 6e shows a significant inhibitory activity against both HDAC6 and Hsp90 with IC50 values of 106 nM and 61 nM, respectively." [PMID:35834905]; developer: "College of Pharmacy, Keimyung University, Daegu, 704-701, South Korea." [PMID:35834905]; stage: "In addition, compound 6e successfully achieved significant tumor growth inhibition in H1975 NSCLC xenograft model without noticeable abnormal behavior, body weight changes, and apparent ocular toxicity." [PMID:35834905]

02

Targets

HDAC6 (Histone deacetylase 6)

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